Mesenchymal stem cells (MSCs) were officially named more than 25 years ago to represent a class of cells from human and mammalian bone marrow and periosteum that could be isolated and expanded in culture while maintaining their in vitro capacity to be induced to form a variety of mesodermal phenotypes and tissues. The in vitro capacity to form bone, cartilage, fat, etc., became an assay for identifying this class of multipotent cells and around which several companies were formed in the 1990s to medically exploit the regenerative capabilities of MSCs. Today, there are hundreds of clinics and hundreds of clinical trials using human MSCs with very few, if any, focusing on the in vitro multipotential capacities of these cells. Unfortunately, the fact that MSCs are called “stem cells” is being used to infer that patients will receive direct medical benefit, because they imagine that these cells will differentiate into regenerating tissue-producing cells. Such a stem cell treatment will presumably cure the patient of their medically relevant difficulties ranging from osteoarthritic (bone-on-bone) knees to various neurological maladies including dementia. I now urge that we change the name of MSCs to Medicinal Signaling Cells to more accurately reflect the fact that these cells home in on sites of injury or disease and secrete bioactive factors that are immunomodulatory and trophic (regenerative) meaning that these cells make therapeutic drugs in situ that are medicinal. It is, indeed, the patient’s own site-specific and tissue-specific resident stem cells that construct the new tissue as stimulated by the bioactive factors secreted by the exogenously supplied MSCs. Stem Cells Translational Medicine 2017;6:1445-1451.
Allogeneic umbilical cord-derived mesenchymal stem cells, exosomes, peptides, platelet-rich plasma, hyaluronic acid, cytokines, growth factors and other forms of regenerative medicine allow the body to repair and replenish any sort of diseased tissue. It’s almost like an “organ transplant” but for your cells. When cells are diseased, they can wreak havoc on your overall health. And instead of using traditional medicine that tries to treat the symptoms associated with damaged cells, regenerative medicine actually attempts to repair and replace the cells themselves.
Where do allogeneic umbilical cord derived mesenchymal stem cells come from?
There are different types of stem cells out there in the world – the point of this article is simply to inform you about these types of stem cells. Not to claim to treat any diseases.
There are allogeneic umbilical cord derived mesenchymal stem cells, adult stem cells, perinatal stem cells, and more.
Researchers “grow” stem cells using highly advanced (and safe) techniques. What’s great about this highly targeted form of “growing” stem cells is that the researchers can grow different types of stem cells to serve different purposes. For example, they can “grow” stem cells that are designed to help with heart muscle cells, brain cells, tissue cells, the cells in your eyes, and more.
These allogeneic umbilical cord derived mesenchymal stem cellsbe implanted into a person. Usually, the they’re injected into the area of the body that needs help.